isosterism是什么意思，isosterism的意思翻译、用法、同义词、例句
isosterism英标
英:/',aɪsəʊ'sterɪzəm/
常用词典
[物] 同电子排列性
网络扩展资料
Isosterism（同位素效应）refers to the phenomenon of two or more molecules having similar molecular shapes and electronic structures, but different chemical compositions. This term is often used in organic chemistry and drug design.
Definition
Isosterism is a concept in chemistry where atoms, ions, or molecules can be replaced with other atoms, ions, or molecules that have similar physical and chemical properties. This replacement is done in order to achieve a similar biological activity or chemical behavior. The term "isostere" refers to the replacement atom or group that has similar properties.
Example
For example, in drug design, a molecule that contains a particular functional group may be replaced with another molecule that has a similar functional group but different chemical composition. This is done in order to alter the molecule's properties, such as its solubility or stability, while maintaining its biological activity.
Another example is the replacement of oxygen with sulfur in some organic compounds. Sulfur has similar properties to oxygen, but the resulting compound may have different properties due to the change in electronegativity.
Pronunciation
[ˌaɪsəʊˈtɛrɪzəm]
Part of Speech
Noun
Usage
Isosterism is a concept mainly used in organic chemistry and drug design.
Explanation
Isosterism is used to modify or optimize the properties of molecules, such as their solubility, stability, or biological activity. This concept is also used to design new drugs that have similar chemical structures but different pharmacological properties.
Synonyms
There are no commonly used synonyms for isosterism.
Antonyms
There are no commonly used antonyms for isosterism.