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[生化] 醛脫氫酶
China's recent stu***s have shown that the mutation of aldehyde dehydrogenase with coronary heart disease and diabetes.
中國最近的研究表明,這個突變的乙醛脫氫酶還與冠心病和糖尿病有關。
Aldehyde dehydrogenase(ALDH) is a kind of endoenzyme and cell-breaking is one of the key procedures in the extraction of ALDH from S. cerevisiae.
乙醛脫氫酶(ALDH)是一種胞内酶,在從酵母中分離提取ALDH的過程中,破碎細胞是其中的關鍵步驟之一。
BADH gene encodes for betaine aldehyde dehydrogenase, an important enzyme for the biosynthesis of glycine betaine that plays a definite role in stress tolerance through osmoregulation.
BADH是甜菜堿乙醛脫氫酶的編碼基因,該酶是甜菜堿生物合成的一種關鍵酶,甜菜堿通過滲透調節發揮抗逆作用。
The activity of aldehyde dehydrogenase (ALD6) of saccharomyces cerevisiaes controls the content of acetic acid in beer.
釀酒酵母中乙醛脫氫酶(ALD6)活性的高低控制着啤酒中乙酸含量的多少。
To find out a method which is more convenient, cost-saving and enough accurate to detect genotypes of alcohol dehydrogenase 2 (ADH2)and aldehyde dehydrogenase 2 (ALDH2).
為獲得更為簡便經濟同時精确度足夠高的酒精脫氫酶2 (ADH2 )和乙醛脫氫酶2 (ALDH2 )基因多态型測定的新方法。
But you do not forget that half of the Chinese people with the mutation of aldehyde dehydrogenase.
可您别忘了,中國人一半帶有突變的乙醛脫氫酶。
Objective:To study the relationship between aldehyde dehydrogenase-2(ALDH2) G1951A gene polymorphism and obstructive sleep apnea hypopnea syndrome(OSAHS) in male drinkers.
目的:了解男性飲酒者乙醛脫氫酶(ALDH2)基因G1951A多态性與阻塞性睡眠呼吸暫停低通氣綜合征(OSAHS)的關系。
Aldehyde dehydrogenase (ALDH) superfamily is a group of enzymes metabolizing endogenous and exogenous aldehydes.
乙醛脫氫酶(ALDH)超家族是一組促進外源和内源乙醛代謝的酶。
Aldehyde dehydrogenase is a kind of endoenzyme, and cell disruption is the major step in its extraction from Saccharomyces ceravisia.
乙醛脫氫酶(ALDH)是一種胞内酶,在從酵母中分離提取ALDH的過程中,破碎細胞是其中的關鍵步驟之一。
Aldehyde Dehydrogenase, from Yeast;
乙醛脫氫酶(酵母);
Extraction of Alcohol Dehydrogenase and Aldehyde Dehydrogenase from Saccharomyces cerevisiae and their Expression by Prokaryotic System …
酵母菌乙醇脫氫酶與乙醛脫氫酶之抽取及其在原核系統之表達 。
Aldehyde dehydrogenase 1(ALDH1);
乙醛脫氫酶1;
醛脫氫酶(Aldehyde Dehydrogenase,簡稱ALDH)是一類廣泛存在于生物體内的氧化還原酶,其主要功能是催化醛類化合物(如甲醛、乙醛等)轉化為相應的羧酸,同時将煙酰胺腺嘌呤二核苷酸(NAD⁺)還原為NADH。這類酶在代謝解毒、能量生成和細胞保護中發揮關鍵作用。
ALDH通過兩步反應完成醛的氧化:首先,醛底物與酶的活性位點結合,NAD⁺作為輔因子接受氫離子形成NADH;隨後,水分子攻擊醛的羰基碳,生成羧酸産物。例如,乙醛脫氫酶(ALDH2)在酒精代謝中将有毒的乙醛轉化為無毒的乙酸,防止乙醛蓄積導緻的細胞損傷。
人類基因組中已發現19種ALDH同工酶,根據亞細胞定位分為胞質型(如ALDH1A1)和線粒體型(如ALDH2),其底物特異性與活性位點的氨基酸殘基排列密切相關。
參考文獻
Aldehyde Dehydrogenase(醛脫氫酶) 是一種關鍵的氧化還原酶,主要功能是催化醛類物質脫氫生成羧酸。以下是詳細解釋:
醛脫氫酶屬于脫氫酶家族,其核心活性位點在不同類别中高度保守,盡管亞基的氨基酸數量可能變化,但催化功能保持穩定。它能将醛類(如乙醛)氧化為相應的羧酸(如乙酸),同時将NAD⁺還原為NADH。
提示:如需具體亞型或病理機制的完整文獻,可參考來源、5、6、9、11。
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