學習工具
n. 原位雜交
As a tissue, cell body fixed ideal CD for the in situ hybridization and immunohistochemical analysis.
作為組織切片、細胞固定的理想裁體，用於原位雜交、免疫組化分析。
This paper introduced the advancement of early diagnosis and prognosis monitoring by fluorescence in situ hybridization in bladder cancer.
本文介紹了熒光原位雜交技術在膀胱癌早期診斷及預後監測應用中的研究進展。
Objective To explore the value of multiplex fluorescence in situ hybridization (M-FISH) technique in the detection of the complex chromosomal aberrations (CCAs) in myelodysplastic syndromes (MDS).
目的探讨多重熒光原位雜交（M-FISH）技術在骨髓增生異常綜合征（MDS）患者複雜核型異常檢測中的應用價值。
The particular nature and the unique properties of these molecules make their use a promising procedure for in situ hybridization assays.
這些分子特殊的性質與獨有的屬性為原位雜交分析提供了一個很有前景的方法。
Conclusion In situ hybridization method established in this study showed showed specificity and sensitivity.
結論本實驗所建立的原位雜交方法具較高特異性和靈敏性。
Objective To investigate the value of multiplex fluorescence in situ hybridization(M-FISH) in the detection of complex chromosomal abnormalities(CCAs) of chronic lymphocytic leukemia(CLL).
目的探讨多重熒光原位雜交（M-FISH）技術檢測慢性淋巴細胞白血病（CLL）複雜核型異常（CCA）的價值。
Methods The expressions of PRX 2, HOXB13, HOX2.2 and HOX2.3 during wound healing in fetal and ***** skin were determined with in situ hybridization.
方法采用原位雜交方法，對正常成人和胎兒皮膚及創面愈合過程中PRX2、HOXB13、HOX2.2和HOX2.3的表達進行觀察。
Objective To evaluate the diagnostic value of fluorescence in situ hybridization (FISH) in sex chromosome abnormality.
目的探讨熒光原位雜交（FISH）技術在性染色體異常診斷中的價值。
Abbott is a pioneer in the use of molecular tests based on PCR and fluorescence in situ hybridization (FISH) technologies to aid clinicians in the selection of appropriate pharmacogenomic therapies.
基於PCR和熒光原位雜交（FISH）技術的分子檢測手段，用以幫助臨床醫生選擇恰當的藥物遺傳學方法治療，雅培在這方面是先行者。
Genomic in situ hybridization (GISH) technique is a most effective method of detecting alien chromatin at molecular level. The probe used in this technique is genomic DNA.
基因組原位雜交是在分子水平上檢測外源染色質的一種有效方法，其探針是總基因組DNA 。
The positive signals of immunohistochemistry and in situ hybridization were mostly located in cytoplasm of monocyte-macrophage system.
免疫組化和原位雜交陽性信號多位於單核巨噬細胞系統胞漿内。
Method:Non isotope in situ hybridization.
方法：非同位素原位雜交。
Chromosome in situ hybridization is one of the most direct and convenient approaches in gene locations.
染色體原位雜交技術是基因定位研究中最為直接和簡便的方法之一。
The chromosome in situ hybridization is an important part in modern biotechnology.
染色體原位雜交技術是現代生物技術的重要組成部分。
Objective To explore the value of interphase fluorescence in situ hybridization(I-FISH) on the detection of trisomy 8 in chronic myeloid leukemia(CML) and the progression of CML.
目的探讨間期熒光原位雜交（I-FISH）技術檢測慢性髓系白血病（CML）8號染色體三體（8三體）異常的價值及其對CML演進監測的意義。
Results (1)in situ hybridization showed that all the 6 retinoic acid receptor genes were expressed in lymphocytes and reticular cells of lymph node, the distribution was widespread.
結果：1。原位雜交結果顯示6種視黃酸受體基因在淋巴結中的淋巴細胞和網狀細胞中均有表達，分布廣泛。
Tissue microarrays are very useful in the investigation of the expression of a particular gene in hundreds of specimens by in situ hybridization.
組織微陣列在通過原位雜交進行的數百個樣本的一個特定基因的研究中是非常有用的。
The technique of digoxigenin labeled probe in situ hybridization is a new specific method in studying the location, distribution and infection mechanisms of SV40 DNA.
*********标記探針原位雜交技術，是探讨SV40病毒核酸在組織中定位、分布和感染機制的一種新的特異性方法。
It indicates that immunohistochemistry and in situ hybridization can provide reliable basis in diagnosis and pathological mechanism study of Q fever.
結果提示免疫組化和原位雜交技術可以作為Q熱特異性的診斷方法，并為緻病機理的研究提供線索。
Fluorescence in situ hybridization (FISH) is a supplement and development of chromosome banding technique.
熒光原位雜交（FISH）是染色體顯帶技術的補充和發展。
Methods The expression of VEGF in 11 normal adrenal gland, 24 benign adrenal pheochromocytomas, and 11 malignant pheochromocytomas was detected by immunohistochemistry and in situ hybridization.
方法用免疫組化和原位雜交研究24例良性腎上腺嗜鉻細胞瘤、11例惡性腎上腺嗜鉻細胞瘤及11例正常腎上腺組織中VEGF的表達情況。
Objective To detect BCR/ABL fusion genes of interphase cells by fluorescence in situ hybridization(FISH) as an assistant way of diagnosis and treatment of chronic myelogenous leukemia (CML).
目的建立熒光原位雜交（FISH）技術，直接原位檢測間期細胞中BCR/ABL融合基因，輔助臨床診斷和治療慢性粒細胞性白血病（CML）。
Some of the 9 types have been identified as alien addition lines through cytology techniques and in situ hybridization of nuclear acids.
這9個類型中有的結合細胞學鏡檢與核酸原位雜交技術已确定為異附加系。
Methods Immunohistochemistry and in situ hybridization technique were adopted.
方法采用免疫組化及原位雜交技術。
The genomic in situ hybridization showed that there are chromosomes or chromosome fragments of Elymus dahuricus in BC1F4.
經基因組原位雜交鑒定，BC1F4代中有披堿草的染色體組或染色體片段。
原位雜交（in situ hybridization） 是一種在細胞或組織切片内，直接在形态學背景下定位特定核酸序列（DNA或RNA）位置的分子生物學技術。其核心原理是利用标記的核酸探針，通過堿基互補配對原則，與細胞内待檢測的靶核酸序列進行特異性雜交，并通過檢測标記信號來确定靶序列的存在位置和相對豐度。
技術原理：
主要類型：
核心應用：
關鍵優勢：
原位雜交是一種強大的技術，通過在細胞或組織的原始位置（in situ）進行核酸雜交，實現了在形态學背景下對特定DNA或RNA序列的定位和半定量分析。它在基礎研究（基因功能、發育）、臨床診斷（遺傳病、腫瘤、感染）等領域具有不可替代的價值。FISH和CISH是其目前最常用的兩種形式。根據專業文獻。
in situ hybridization（原位雜交） 是一種分子生物學技術，用於在細胞或組織樣本中定位特定核酸序列（如DNA或RNA）的精确位置。以下是詳細解釋：
定義與原理
技術特點
主要應用
技術變體
該技術通過“原位”檢測核酸，為基因功能、疾病機制等研究提供了空間層面的關鍵信息。如需進一步了解操作步驟或具體案例，可參考分子生物學實驗手冊或專業數據庫。
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